Z-Wave network reliability

This is not the reason, it just says that the last used known route is Unknown since last reboot (and older then xx hours, unsure how old it has to be), nothing more nothing less.
It is also doesn’t mean it is the route, it is just a route that was used last.

Homey can’t just brick a device, if a device bricks then that is a device issue, and you should pick this up with Fibaro themselves.
The only thing Homey does to “reset a device” is respond it’s NIF (netwerk identification frame, or in regular wording, it’s internal ID’s and the capabilities it has), if the device is in the exclusion mode it will reset itself to manufacturers default.
The device has nothing to do with this information, it is just an “ok” as confirmation to reset, so it isn’t an accidental reset.

See issue 1 as it is completely the same.

So to help you any further, take care of the interference, and only if that fails, then, and only then say anything about resetting anything.

S2 security doesn’t have a lot of overhead in terms of speed, so it is all up to you if you want devices to be unsecure or not.