AMU-500 only works when manually pressing twice with about a 2s interval

This is normal for KAKU and many other 433 devices,
As it is one way the sender doesn’t know if reception was OK.
So most send the signal just ~20 times,
To differentiate between signals a silence is required, Before the next signal can be processed.
an ASUN-650 for an Roler shutter also cant be stoppped within ~2 seconds.

For analyzing pls look at an old post from me:

It is not Homey, it is just a limitation of KAKU / most 433 devices.

Just switch to something real like Z-Wave or Zigbee, I managed to let a Fibaro switch a TradFri I wanted to reset 6 times on for les than 0.2 seconds repeated that 6 times with ~2 seconds interval.